ol. 7 No. 1 (2025) Advances in biomarkers, therapeutics, and probiotics: Recent updates in medical laboratories

Recent discoveries underscore the promise of betatrophin and GAD65 in metabolic screening, rosella extract’s antibacterial efficacy, and fibrinolytic protease HSFT-2’s anticoagulant potential. Vitamin D enhances mesenchymal stem cell properties, while traditional yogurts offer superior probiotic benefits. These findings illuminate innovative pathways for disease prevention and therapeutic development.

The articles in this issue were authored/co-authored by authors India and Indonesia

1. Betatrophin: A promising biomarker for metabolic syndrome and diabetes mellitus risk screening in teenagers
2. Spectroscopic characterization of rosella flower extract (Hibiscus sabdariffa L.) and its antibacterial activity against Enterobacter aerogenes in suspected typhoid cases
3. In vitro anticoagulant activity of crude fibrinolytic protease HSFT-2 as an alternative anticoagulant agent
4. The clinical value of systemic immune-inflammation index (SII) and prognostic nutritional index (PNI) for predicting the occurrence of metastasis in patients with lung cancer
5. Significance of serum protein electrophoresis in diagnosing multiple myeloma: A retrospective study at a tertiary care centre
6. Vitamin D enhances migration but decreases gene expression of vascular endothelial growth factor and tumor necrosis factor-α in Wharton’s jelly mesenchymal stem cells
7. Quality assessment and biochemical characterization of probiotic Lactobacillus species isolated from yogurts fermented either by Tamarindus indica or Capsicum annuum
8. Exploration and molecular identification of proteolytic bacteria from rusip pacific oyster (Crassostrea gigas) as anticoagulant agent candidates