Journal of Biomedicine and Translational Research (JBTR) is an open access, international peer-reviewed journal that considers articles on: clinical medicine, molecular medicine, tropical medicine, infectious diseases, cardiovascular medicine, molecular biology, genetics, immunology, microbiology, biochemistry, and pharmacotherapy with particular interest on the link between clinical and basic research called translational research. The journal publishes articles on a wide range of subjects of interest to researchers and clinical practitioners. Papers from any institution related to the field above are welcome, collaborative research is more appreciated.

In the present time, due to rapid progress of genomic research and medical services globally, the JBTR have collaborated scientifically with Indonesian Society of Human Genetics (InaSHG) and Indonesian Society of Internal Medicine (PAPDI) Semarang branch by inviting members of InaSHG and PAPDI to be a member of editorial board and advisory board as well as reviewers.

Table of Contents
Original Research Articles

1. Increased Level of The Plasminogen Activator Inhibitor Type-1 is Associated with Severity of NAFLD
Didik Indiarso, Agung Prasetyo, Hirlan Hirlan, Hery Djagat Purnomo

2. Molecular Detection Challenges of Human Plasmodium Knowlesi Infection by Polymerase Chain Reaction and Sequencing
Erma Sulistyaningsih, Resy Metri Belizani, Irawan Fajar Kusuma, Sahrir Sillehu, Rosita Dewi

3. Potential Effects of Ipomoea reptans Poir. Extract on LDL, HDL levels and liver Histopathology
Kartika Rahma, Frida Octavia Purnomo

4. The Activity of Liposome-Parijoto Formula Through p53 Expression in HepG2 Cell Line
widyandani sasikirana, Ragil Setia Dianingati, Khairul Anam, eva annisaa', evieta Rohana

5. BALB/c Mice as Animal Model in Dengue Infection Research: Role of Endothelial Activation
I Made Susila Utama, Tuti Parwati Merati, Made Bakta, Made Jawi

6. Effect Of Zinc Administration in Preventing Ethambutol-Induced Optic Neuropathy in Wistar Rats Model
Riski Prihatningtias, Disti Hardiyanti, Maharani Maharani, Arief Wildan, Arnila Novitasari Saubig, Hermawan Istiadi

Case Reports
7. Plasma Exchange as A Rescue Therapy in Weil’s Disease with Severe Hyperbilirubinemia, Acute Renal Failure, And Multidrug-Resistant Organism Co-Infection: A Rare Case in Critical Care Setting
Debby Vania, Albert Frido Hutagalung

Review Articles
8. Mechanism of Immune System Dysfunction, Apoptosis and Oxidative Stress on Endometriosis
Miftahuz Zakiyah, Asmarinah Asmarinah