The Indonesian Biomedical Journal (lnaBJ) is an open access, peer-reviewed journal that encompasses all fundamental and molecular aspects of basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms. lnaBJ is dedicated to publishing original research and review articles covering all aspects of biomedical sciences. While authors from any affiliations and country are welcomed to submit original research articles; however, review articles can only be submitted by invited authors.

InaBJ is published by the Prodia Education and Research Institute. lnaBJ has been indexed by Scopus, Clarivate, DOAJ, etc, and also has been accredited by Ministry of Education, Culture, Research and Technology of the Republic of Indonesia.

Vol 17, No 2 (2025)
Table of Contents
Review Article
Resveratrol: The Multifaceted Roles and Mechanisms of Polyphenol to Improve Longevity, Immunomodulation, and Age-related Diseases
Anna Meiliana, Nurrani Mustika Dewi, Andi Wijaya

Research Article
1. Insulin Resistance, Adiponectin, and Dyslipidemia as Key Determinants of Metabolic and Reproductive Dysregulation in Polycystic Ovary Syndrome
Krarr Haider Haddawi, Bushra Raouf Yaseen, Redha Dawud Abd Alredha, Kareem Obayes Handool

2. miR-29 Family as Epigenetic Regulators of DNMTs in Prostate Cancer and Benign Prostatic Hyperplasia
Yudi Gebri Foenna, Nilüfer Şahin Calapoğlu, Okan Sancer, Muhammet Yusuf Tepebaşı, Mustafa Calapoğlu

3. N-Acetylcysteine Prevents Sleep Deprivation-induced Memory Deficit in Juvenile Rats Through the Suppression of BDNF, Cortisol, Acetylcholine Levels, and Inflammatory Cytokines Expressions
Citra Rosyidah, Wawaimuli Arozal, Hee Jae Lee, Raymond Rubianto Tjandrawinata, Wahyunia Likhayati Septiana

4. Lower IGF-1 and Alkaline Phosphatase Activity Blood Levels in Stunted Children with Soil-Transmitted Helminth Infections
Tiara Mayang Pratiwi Lio, Heri Wibowo, Mohamad Sadikin, Sri Widia A. Jusman

5. MCM6 rs4988235 Allele G, AGT rs699 Allele C, ACE rs4343 Allele A, FADS1 rs174547 Allele C, DCHR7 rs12785878 Allele G, and GC rs7041 Allele T: Candidate Genes for Preeclampsia Prevention
Deviana Soraya Riu, Isharyah Sunarno, Efendi Lukas

6. Alpha-Actinin-3 (ACTN3) R577X Polymorphism on Brain-derived Neurotrophic Factor (BDNF) Levels of Pre- and Post-Eccentric Exercised Male Subjects
Audira Syafana Khadijah, Aurel Aryati, Aurel Diffa Arpy, Angela Excellcia Larasaty Susetyo, Monica Dwi Hartanti

7. Elevation of miR-210 Expression and Mean Arterial Pressure as Early-onset Pre-eclampsia Biomarkers, while Elevation of Matrix Metalloproteinase-2 as Late-onset Pre-eclampsia Biomarker
Nelvianti Nelson, Yusrawati Yusrawati, Joserizal Serudji, Jamsari Jamsari, Arni Amir, Afriwardi Afriwardi, Erry Gumilar

8. FGFR2 as A Prognostic and Predictive Marker in Colorectal Adenocarcinoma Based on TILs Grade
Andi Marcha Rianti, Muhammad Husni Cangara, Amalia Yamin, Haslindah Dahlan, Muhammad Riza Ilyasa, Upik Anderiani Miskad

9. Intermittent Exposure to Hypobaric Hypoxia Increases VEGF, HIF-1α, and Nrf-2 Expressions in Brain Tissue
Wardaya Wardaya, Dewi Sukmawati, Nurhadi Ibrahim, Frans Ferdinal, Ninik Mudjihartini, Mohamad Sadikin, Sri Widia A. Jusman, Irawan Satriotomo, Wawan Mulyawan