EBOOK TLM
Mucosal Immunology and Virology
Three vaccines were recently approved
by the United States Food and Drug
Administration. Two of these vaccines,
RotaTeq and Gardasil, stimulate mucosal
immunity. RotaTeq is an oral pentavalent
vaccine approved for prevention of
rotavirus infection, the most important
cause of severe infantile gastroenteritis
worldwide. Gardasil is a quadrivalent
(injectable) vaccine approved for prevention
of human papillomavirus (HPV)
types 16 and 18, the leading causes of
cervical cancer worldwide, as well as for prevention of HPV types 6 and 11, the
leading causes of condyloma acuminatum.
The third,recently-approved vaccine
is Zostavax which will be used for the prevention
of herpes zoster and postherpetic
neuralgia. Therefore, this vaccine will not
be used in the classic sense as a prophylactic
vaccine, but rather will be given to
prevent the clinical reappearance of virus
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