The Indonesian Biomedical Journal (lnaBJ) is an open access, peer-reviewed journal that encompasses all fundamental and molecular aspects of basic medical sciences, emphasizing on providing the molecular studies of biomedical problems and molecular mechanisms. lnaBJ is dedicated to publishing original research and review articles covering all aspects of biomedical sciences. While authors from any affiliations and country are welcomed to submit original research articles; however, review articles can only be submitted by invited authors.

InaBJ is published by the Prodia Education and Research Institute. lnaBJ has been indexed by Scopus, Clarivate, DOAJ, etc, and also has been accredited by Ministry of Education, Culture, Research and Technology of the Republic of Indonesia.

Vol 17, No 5 (2025)

Table of Contents

Research Article

1. Aluminum Exposure Induces Time-Dependent Cognitive Decline, Anxiety, and Brain Aluminum Accumulation in Rats
Amirul Hafiz Ahmad Abdullah, Husna Anuar, Nur Afiqha Rosli, Hilal Haiqal Faizal, Kalaimathy Moothy, Muhammad Hafiz Zuhdi Fairof, Nurul Farhana Jufri, Siti Fathiah Masre, Nor Fadilah Rajab, Farah Wahida Ibrahim

2. Genotype Combination of rs1042044 and rs6458093 in GLP-1R as A Genetic Risk for Osteoporosis in Postmenopausal Iraqi Women
Ammar Kadhim Alzubaidi, Farah Abdulwahab Al-Saadi, Amer Qani Alagele

3. Long Noncoding RNAs TYMSOS, VASH1-AS1, and LINC01001 Expressions as Biomarkers of β-thalassaemia Severity Among the Malaysian Patients
Norafiza Mohd Yasin, Nur Fatin Aqilah Raman, Siti Aishah Sulaiman, Nurhairulamri Kosnan, Nor Azian Abdul Murad, Ermi Neiza Mohd Sahid, Yuslina Yusoff, Hishamshah Mohd Ibrahim, Zulaiha Muda, Ezalia Esa

4. Low Serum Nerve Growth Factor Levels Are Associated with Insulin Resistance, Beta Cell Dysfunction, and Neuropathy Screening Scores in Subjects with Type 2 Diabetes Mellitus
Dhini Sylvana, Dharma Lindarto, Santi Syafril

5. Modified High-Fat High-Sucrose Diet Promotes Obesity and Alters Colonic Cytokines
Bernadette Dian Novita, I Gede Putu Adhi Wedharga, Yudy Tjahjono, Hendy Wijaya, Imelda Theodora, Martha Ervina, Yufita Ratnasari Wilianto, Sianty Dewi, Irene Lingkan Parengkuan, Herjunianto Herjunianto, Sabrina Maria Ghasani, Michael Christian Limantoro, Ferdinand Wiliam Jaya

6. Quercetin Stabilizes Atherosclerotic Plaques by Reducing Matrix Metalloproteinase-9 Expression and Enhancing M2 Macrophage Activity in Wistar Rats
Romi Ermawan, Budi Susetyo Pikir, Mulyanto Mulyanto, Budi Utomo, Widjiati Widjiati, Yudi Her Oktaviono

7. Inositol Hexakisphosphate (InsP₆) Induces Apoptosis via Caspase-Dependent Pathways: Molecular Docking Insights
Ferry Sandra, Dewi Ranggaini, Johni Halim, Alfred Pakpahan, Visi Endah Pratitis, Kyung Hoon Lee

8. Liposome-based Nanoparticles Encapsulating Vitamin D3 Attenuate IL-6 and TNF-α in a Menopausal Mouse Model
Baskara Wiku Adi Kusuma, Sri Ratna Dwiningsih, Ashon As’adi, Sri Puji Astuti Wahyuningsih

9. Design and Stability Evaluation of Active Peptides from Indonesian Echinozoa as Acetylcholinesterase (AChE) Inhibitors for Alzheimer’s Therapy
Laelatul Afifah, Vania Uly Andyra, Marlyn Dian Laksitorini, Tri Rini Nuringtyas

10. Impact of GFR Stratification on Tc-99m DTPA Dose Distribution in Target and Non-Target Organs: A MIRD-Based Comparative Study in Renogram Imaging
Luthfia Qalby, Wahyu Setia Budi, Eko Hidayanto